The Updating of Biological Functions of Methyltransferase SETDB1 and Its Relevance in Lung Cancer and Mesothelioma

SET domain bifurcated 1 (SETDB1) is a histone H3 lysine 9 (H3K9) methyltransferase that exerts important effects on epigenetic gene regulation. SETDB1 complexes (SETDB1-KRAB-KAP1, SETDB1-DNMT3A, SETDB1-PML, SETDB1-ATF7IP-MBD1) play crucial roles in the processes of histone methylation, transcription...

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Detalles Bibliográficos
Autores principales: Yuan, Li, Sun, Boshu, Xu, Liangliang, Chen, Limin, Ou, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306223/
https://www.ncbi.nlm.nih.gov/pubmed/34299035
http://dx.doi.org/10.3390/ijms22147416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306223/
https://www.ncbi.nlm.nih.gov/pubmed/34299035
http://dx.doi.org/10.3390/ijms22147416

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