Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian Cancer

SIMPLE SUMMARY: Hexokinase II (HKII) is a key glycolysis enzyme associated with tumorigenesis, but its molecular mechanism and pathophysiological role in chemoresistant ovarian cancer remain elusive. In this study, we delineate the novel mechanism showing that activated phosphorylated-p53 (P-p53 Ser...

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Detalles Bibliográficos
Autores principales: Han, Chae Young, Patten, David A., Kim, Se Ik, Lim, Jung Jin, Chan, David W., Siu, Michelle K. Y., Han, Youngjin, Carmona, Euridice, Parks, Robin J., Lee, Cheol, Di, Li-Jun, Lu, Zhen, Chan, Karen K. L., Ku, Ja-Lok, Macdonald, Elizabeth A., Vanderhyden, Barbara C., Mes-Masson, Anne-Marie, Ngan, Hextan Y. S., Cheung, Annie N. Y., Song, Yong Sang, Bast, Robert C., Harper, Mary-Ellen, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306240/
https://www.ncbi.nlm.nih.gov/pubmed/34298618
http://dx.doi.org/10.3390/cancers13143399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306240/
https://www.ncbi.nlm.nih.gov/pubmed/34298618
http://dx.doi.org/10.3390/cancers13143399

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