Cell Reprogramming to Model Huntington’s Disease: A Comprehensive Review

Huntington’s disease (HD) is a neurodegenerative disorder characterized by the progressive decline of motor, cognitive, and psychiatric functions. HD results from an autosomal dominant mutation that causes a trinucleotide CAG repeat expansion and the production of mutant Huntingtin protein (mHTT). T...

Descripción completa

Detalles Bibliográficos
Autores principales: Monk, Ruth, Connor, Bronwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306243/
https://www.ncbi.nlm.nih.gov/pubmed/34206228
http://dx.doi.org/10.3390/cells10071565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306243/
https://www.ncbi.nlm.nih.gov/pubmed/34206228
http://dx.doi.org/10.3390/cells10071565

Ejemplares similares