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Cell Reprogramming to Model Huntington’s Disease: A Comprehensive Review
Huntington’s disease (HD) is a neurodegenerative disorder characterized by the progressive decline of motor, cognitive, and psychiatric functions. HD results from an autosomal dominant mutation that causes a trinucleotide CAG repeat expansion and the production of mutant Huntingtin protein (mHTT). T...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306243/ https://www.ncbi.nlm.nih.gov/pubmed/34206228 http://dx.doi.org/10.3390/cells10071565 |