In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma

Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by systemic toxicity. The main objective of this in vitro study was to determine the anti-tumoral effect (IC(50)) and intracellular accumulation of free and liposomal doxorubicin (DOX) in four human cancer...

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Detalles Bibliográficos
Autores principales: Kullenberg, Fredrik, Degerstedt, Oliver, Calitz, Carlemi, Pavlović, Nataša, Balgoma, David, Gråsjö, Johan, Sjögren, Erik, Hedeland, Mikael, Heindryckx, Femke, Lennernäs, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306283/
https://www.ncbi.nlm.nih.gov/pubmed/34359887
http://dx.doi.org/10.3390/cells10071717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306283/
https://www.ncbi.nlm.nih.gov/pubmed/34359887
http://dx.doi.org/10.3390/cells10071717

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