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Doxycycline Interferes with Zika Virus Serine Protease and Inhibits Virus Replication in Human Skin Fibroblasts

Zika virus (ZIKV) represents a re-emerging threat to global health due to its association with congenital birth defects. ZIKV NS2B-NS3 protease is crucial for virus replication by cleaving viral polyprotein at various junctions to release viral proteins and cause cytotoxic effects in ZIKV-infected c...

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Detalles Bibliográficos
Autores principales: Chong Teoh, Teow, J. Al-Harbi, Sawsam, Abdulrahman, Ammar Yasir, Rothan, Hussin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306286/
https://www.ncbi.nlm.nih.gov/pubmed/34299596
http://dx.doi.org/10.3390/molecules26144321