M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines

Background: Glioblastoma multiforme (GBM) is characterized by several genetic abnormalities, leading to cell cycle deregulation and abnormal mitosis caused by a defective checkpoint. We previously demonstrated that arecaidine propargyl ester (APE), an orthosteric agonist of M2 muscarinic acetylcholi...

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Detalles Bibliográficos
Autores principales: Di Bari, Maria, Tombolillo, Vanessa, Alessandrini, Francesco, Guerriero, Claudia, Fiore, Mario, Asteriti, Italia Anna, Castigli, Emilia, Sciaccaluga, Miriam, Guarguaglini, Giulia, Degrassi, Francesca, Tata, Ada Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306299/
https://www.ncbi.nlm.nih.gov/pubmed/34359896
http://dx.doi.org/10.3390/cells10071727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306299/
https://www.ncbi.nlm.nih.gov/pubmed/34359896
http://dx.doi.org/10.3390/cells10071727

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