Focused Ion Microbeam Irradiation Induces Clustering of DNA Double-Strand Breaks in Heterochromatin Visualized by Nanoscale-Resolution Electron Microscopy

Background: Charged-particle radiotherapy is an emerging treatment modality for radioresistant tumors. The enhanced effectiveness of high-energy particles (such as heavy ions) has been related to the spatial clustering of DNA lesions due to highly localized energy deposition. Here, DNA damage patter...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorat, Yvonne, Reindl, Judith, Isermann, Anna, Rübe, Christian, Friedl, Anna A., Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306362/
https://www.ncbi.nlm.nih.gov/pubmed/34299263
http://dx.doi.org/10.3390/ijms22147638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306362/
https://www.ncbi.nlm.nih.gov/pubmed/34299263
http://dx.doi.org/10.3390/ijms22147638

Ejemplares similares