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Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice

BACKGROUND: Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). MET...

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Detalles Bibliográficos
Autores principales: Lin, Xiuli, Liu, Yingying, Ma, Lili, Ma, Xiaomeng, Shen, Liping, Ma, Xueying, Chen, Zhaoyu, Chen, Hao, Li, Donghong, Su, Zhumin, Chen, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306367/
https://www.ncbi.nlm.nih.gov/pubmed/34301274
http://dx.doi.org/10.1186/s12967-021-02995-z