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Modelling Mitochondrial Disease in Human Pluripotent Stem Cells: What Have We Learned?
Mitochondrial diseases disrupt cellular energy production and are among the most complex group of inherited genetic disorders. Affecting approximately 1 in 5000 live births, they are both clinically and genetically heterogeneous, and can be highly tissue specific, but most often affect cell types wi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306397/ https://www.ncbi.nlm.nih.gov/pubmed/34299348 http://dx.doi.org/10.3390/ijms22147730 |