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Modelling Mitochondrial Disease in Human Pluripotent Stem Cells: What Have We Learned?

Mitochondrial diseases disrupt cellular energy production and are among the most complex group of inherited genetic disorders. Affecting approximately 1 in 5000 live births, they are both clinically and genetically heterogeneous, and can be highly tissue specific, but most often affect cell types wi...

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Detalles Bibliográficos
Autores principales: McKnight, Cameron L., Low, Yau Chung, Elliott, David A., Thorburn, David R., Frazier, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306397/
https://www.ncbi.nlm.nih.gov/pubmed/34299348
http://dx.doi.org/10.3390/ijms22147730