HPV Infection Leaves a DNA Methylation Signature in Oropharyngeal Cancer Affecting Both Coding Genes and Transposable Elements

SIMPLE SUMMARY: The HPV oncoproteins E6 and E7 can modulate the expression and activity of the maintenance DNA methyltransferase 1, suggesting that HPV carcinogenic mechanisms may include aberrant DNA methylation. Some studies previously proposed both gene-associated DNA methylation signatures and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Camuzi, Diego, Buexm, Luisa Aguirre, Lourenço, Simone de Queiroz Chaves, Esposti, Davide Degli, Cuenin, Cyrille, Lopes, Monique de Souza Almeida, Manara, Francesca, Talukdar, Fazlur Rahman, Herceg, Zdenko, Ribeiro Pinto, Luis Felipe, Soares-Lima, Sheila Coelho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306428/
https://www.ncbi.nlm.nih.gov/pubmed/34298834
http://dx.doi.org/10.3390/cancers13143621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306428/
https://www.ncbi.nlm.nih.gov/pubmed/34298834
http://dx.doi.org/10.3390/cancers13143621

Ejemplares similares