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In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response
Germinal centers (GCs) are transient structures in the secondary lymphoid organs, where B cells undergo affinity maturation to produce high affinity memory and plasma cells. The lifetime of GC responses is a critical factor limiting the extent of affinity maturation and efficiency of antibody respon...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306527/ https://www.ncbi.nlm.nih.gov/pubmed/34359906 http://dx.doi.org/10.3390/cells10071736 |