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In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response

Germinal centers (GCs) are transient structures in the secondary lymphoid organs, where B cells undergo affinity maturation to produce high affinity memory and plasma cells. The lifetime of GC responses is a critical factor limiting the extent of affinity maturation and efficiency of antibody respon...

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Detalles Bibliográficos
Autores principales: Arulraj, Theinmozhi, Binder, Sebastian C., Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306527/
https://www.ncbi.nlm.nih.gov/pubmed/34359906
http://dx.doi.org/10.3390/cells10071736