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Sustained Systemic Levels of IL-6 Impinge Early Muscle Growth and Induce Muscle Atrophy and Wasting in Adulthood

IL-6 is a pleiotropic cytokine that can exert different and opposite effects. The muscle-induced and transient expression of IL-6 can act in an autocrine or paracrine manner, stimulating anabolic pathways associated with muscle growth, myogenesis, and with regulation of energy metabolism. In contras...

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Detalles Bibliográficos
Autores principales: Pelosi, Laura, Berardinelli, Maria Grazia, Forcina, Laura, Ascenzi, Francesca, Rizzuto, Emanuele, Sandri, Marco, De Benedetti, Fabrizio, Scicchitano, Bianca Maria, Musarò, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306542/
https://www.ncbi.nlm.nih.gov/pubmed/34359985
http://dx.doi.org/10.3390/cells10071816