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Sustained Systemic Levels of IL-6 Impinge Early Muscle Growth and Induce Muscle Atrophy and Wasting in Adulthood
IL-6 is a pleiotropic cytokine that can exert different and opposite effects. The muscle-induced and transient expression of IL-6 can act in an autocrine or paracrine manner, stimulating anabolic pathways associated with muscle growth, myogenesis, and with regulation of energy metabolism. In contras...
Autores principales: | Pelosi, Laura, Berardinelli, Maria Grazia, Forcina, Laura, Ascenzi, Francesca, Rizzuto, Emanuele, Sandri, Marco, De Benedetti, Fabrizio, Scicchitano, Bianca Maria, Musarò, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306542/ https://www.ncbi.nlm.nih.gov/pubmed/34359985 http://dx.doi.org/10.3390/cells10071816 |
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