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Expression of Connexin43 Stimulates Endothelial Angiogenesis Independently of Gap Junctional Communication In Vitro

Connexins (Cx) form gap junctions (GJ) and allow for intercellular communication. However, these proteins also modulate gene expression, growth, and cell migration. The downregulation of Cx43 impairs endothelial cell migration and angiogenetic potential. Conversely, endothelial Cx43 expression is up...

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Detalles Bibliográficos
Autores principales: Koepple, Christoph, Zhou, Zizi, Huber, Lena, Schulte, Matthias, Schmidt, Kjestine, Gloe, Torsten, Kneser, Ulrich, Schmidt, Volker Jürgen, de Wit, Cor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306600/
https://www.ncbi.nlm.nih.gov/pubmed/34299018
http://dx.doi.org/10.3390/ijms22147400