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Elevated Levels of CTRP1 in Obesity Contribute to Tumor Progression in a p53-Dependent Manner

SIMPLE SUMMARY: Obesity is regarded as a risk factor for various cancers. However, the molecular mechanisms linking obesity with cancer remain primarily uncharacterized. In this study, we demonstrate that CTRP1, an adiponectin paralogue, promotes tumor growth in a p53-dependent manner. Obese mice on...

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Detalles Bibliográficos
Autores principales: Park, Rackhyun, Jang, Minsu, Park, Yea-In, Park, Yeonjeong, Namkoong, Sim, Lee, Jin I., Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306638/
https://www.ncbi.nlm.nih.gov/pubmed/34298831
http://dx.doi.org/10.3390/cancers13143619