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Trehalose Reduces the Secreted Beta-Amyloid Levels in Primary Neurons Independently of Autophagy Induction

The disaccharide trehalose was described as possessing relevant neuroprotective properties as an mTORC1-independent inducer of autophagy, with the ability to protect cellular membranes and denaturation, resulting from desiccation, and preventing the cellular accumulation of protein aggregates. These...

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Detalles Bibliográficos
Autores principales: Benito-Cuesta, Irene, Ordoñez-Gutierrez, Lara, Wandosell, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306653/
https://www.ncbi.nlm.nih.gov/pubmed/34206776
http://dx.doi.org/10.3390/metabo11070421