Cargando…

Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment

SIMPLE SUMMARY: Despite extensive research, malignant glioma remains the most aggressive and fatal type of brain tumor. Following resection, therapy is based on radiation concomitant with the methylating agent temozolomide (TMZ), followed by adjuvant high-dose TMZ. In previous work, we showed that f...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwarzenbach, Christian, Tatsch, Larissa, Brandstetter Vilar, Juliana, Rasenberger, Birgit, Beltzig, Lea, Kaina, Bernd, Tomicic, Maja T., Christmann, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306656/
https://www.ncbi.nlm.nih.gov/pubmed/34298797
http://dx.doi.org/10.3390/cancers13143585