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Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment
SIMPLE SUMMARY: Despite extensive research, malignant glioma remains the most aggressive and fatal type of brain tumor. Following resection, therapy is based on radiation concomitant with the methylating agent temozolomide (TMZ), followed by adjuvant high-dose TMZ. In previous work, we showed that f...
Autores principales: | Schwarzenbach, Christian, Tatsch, Larissa, Brandstetter Vilar, Juliana, Rasenberger, Birgit, Beltzig, Lea, Kaina, Bernd, Tomicic, Maja T., Christmann, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306656/ https://www.ncbi.nlm.nih.gov/pubmed/34298797 http://dx.doi.org/10.3390/cancers13143585 |
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