A Regulator Based “Semi-Targeted” Approach to Activate Silent Biosynthetic Gene Clusters

By culturing microorganisms under standard laboratory conditions, most biosynthetic gene clusters (BGCs) are not expressed, and thus, the products are not produced. To explore this biosynthetic potential, we developed a novel “semi-targeted” approach focusing on activating “silent” BGCs by concurren...

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Detalles Bibliográficos
Autores principales: Mingyar, Erik, Mühling, Lucas, Kulik, Andreas, Winkler, Anika, Wibberg, Daniel, Kalinowski, Jörn, Blin, Kai, Weber, Tilmann, Wohlleben, Wolfgang, Stegmann, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306873/
https://www.ncbi.nlm.nih.gov/pubmed/34299187
http://dx.doi.org/10.3390/ijms22147567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306873/
https://www.ncbi.nlm.nih.gov/pubmed/34299187
http://dx.doi.org/10.3390/ijms22147567

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