Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer Leading to Reductions in Immunosuppressive Subsets and Tumor Growth

SIMPLE SUMMARY: The deposition of fibrotic tissue within pancreatic tumors acts as a physical barrier to therapeutic treatment. Collagen constitutes a large part of this barrier and serves as an ideal target to improve delivery and efficacy of anti-cancer treatments. This study characterizes a novel...

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Detalles Bibliográficos
Autores principales: Ebelt, Nancy D., Zamloot, Vic, Zuniga, Edith, Passi, Kevin B., Sobocinski, Lukas J., Young, Cari A., Blazar, Bruce R., Manuel, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306875/
https://www.ncbi.nlm.nih.gov/pubmed/34298778
http://dx.doi.org/10.3390/cancers13143565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306875/
https://www.ncbi.nlm.nih.gov/pubmed/34298778
http://dx.doi.org/10.3390/cancers13143565

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