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In Situ Monitored Vortex Fluidic-Mediated Protein Refolding/Unfolding Using an Aggregation-Induced Emission Bioprobe

Protein folding is important for protein homeostasis/proteostasis in the human body. We have established the ability to manipulate protein unfolding/refolding for β-lactoglobulin using the induced mechanical energy in the thin film microfluidic vortex fluidic device (VFD) with monitoring as such usi...

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Detalles Bibliográficos
Autores principales: Hu, Qi, Hu, Haozhen, Zhang, Xinyi, Fan, Kyle, Hong, Yuning, Raston, Colin L., Tang, Youhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306882/
https://www.ncbi.nlm.nih.gov/pubmed/34299548
http://dx.doi.org/10.3390/molecules26144273