Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from Nectandra leucantha

In the present study, the phytochemical study of the n-hexane extract from flowers of Nectandra leucantha (Lauraceae) afforded six known neolignans (1–6) as well as one new metabolite (7), which were characterized by analysis of NMR, IR, UV, and ESI-HRMS data. The new compound 7 exhibited potent act...

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Detalles Bibliográficos
Autores principales: Araujo, Sheila C., Sousa, Fernanda S., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G., Honorio, Kathia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306904/
https://www.ncbi.nlm.nih.gov/pubmed/34299391
http://dx.doi.org/10.3390/molecules26144116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306904/
https://www.ncbi.nlm.nih.gov/pubmed/34299391
http://dx.doi.org/10.3390/molecules26144116

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