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Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from Nectandra leucantha
In the present study, the phytochemical study of the n-hexane extract from flowers of Nectandra leucantha (Lauraceae) afforded six known neolignans (1–6) as well as one new metabolite (7), which were characterized by analysis of NMR, IR, UV, and ESI-HRMS data. The new compound 7 exhibited potent act...
Autores principales: | Araujo, Sheila C., Sousa, Fernanda S., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G., Honorio, Kathia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306904/ https://www.ncbi.nlm.nih.gov/pubmed/34299391 http://dx.doi.org/10.3390/molecules26144116 |
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