Lysophosphatidic Acid Receptor Antagonists and Cancer: The Current Trends, Clinical Implications, and Trials

Lysophosphatidic acid (LPA) is a bioactive lipid mediator primarily derived from membrane phospholipids. LPA initiates cellular effects upon binding to a family of G protein-coupled receptors, termed LPA receptors (LPAR1 to LPAR6). LPA signaling drives cell migration and proliferation, cytokine prod...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Hsuan, Lin, Yueh-Chien, Chen, Chien-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306951/
https://www.ncbi.nlm.nih.gov/pubmed/34209775
http://dx.doi.org/10.3390/cells10071629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306951/
https://www.ncbi.nlm.nih.gov/pubmed/34209775
http://dx.doi.org/10.3390/cells10071629

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