Non-Covalent Binding of Tripeptides-Containing Tryptophan to Polynucleotides and Photochemical Deamination of Modified Tyrosine to Quinone Methide Leading to Covalent Attachment

A series of tripeptides TrpTrpPhe (1), TrpTrpTyr (2), and TrpTrpTyr[CH(2)N(CH(3))(2)] (3) were synthesized, and their photophysical properties and non-covalent binding to polynucleotides were investigated. Fluorescent Trp residues (quantum yield in aqueous solvent Φ(F) = 0.03–0.06), allowed for the...

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Detalles Bibliográficos
Autores principales: Erben, Antonija, Sviben, Igor, Mihaljević, Branka, Piantanida, Ivo, Basarić, Nikola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306964/
https://www.ncbi.nlm.nih.gov/pubmed/34299591
http://dx.doi.org/10.3390/molecules26144315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306964/
https://www.ncbi.nlm.nih.gov/pubmed/34299591
http://dx.doi.org/10.3390/molecules26144315

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