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TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway

Background: TREM2 expressed on microglia plays an important role in modulating inflammation in neurodegenerative diseases. It remains unknown whether TREM2 modulates hyperglycemia-induced microglial inflammation. Methods: We investigated the molecular function of TREM2 in high glucose-induced microg...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Long, Weihong, Gao, Menghan, Jiao, Fangtai, Chen, Zecai, Liu, Mingyuan, Yu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306970/
https://www.ncbi.nlm.nih.gov/pubmed/34356130
http://dx.doi.org/10.3390/brainsci11070896