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Lipoprotein Proteomics and Aortic Valve Transcriptomics Identify Biological Pathways Linking Lipoprotein(a) Levels to Aortic Stenosis

Lipoprotein(a) (Lp(a)) is one of the most important risk factors for the development of calcific aortic valve stenosis (CAVS). However, the mechanisms through which Lp(a) causes CAVS are currently unknown. Our objectives were to characterize the Lp(a) proteome and to identify proteins that may be di...

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Detalles Bibliográficos
Autores principales: Bourgeois, Raphaëlle, Bourgault, Jérôme, Despres, Audrey-Anne, Perrot, Nicolas, Guertin, Jakie, Girard, Arnaud, Mitchell, Patricia L., Gotti, Clarisse, Bourassa, Sylvie, Scipione, Corey A., Gaudreault, Nathalie, Boffa, Michael B., Koschinsky, Marlys L., Pibarot, Philippe, Droit, Arnaud, Thériault, Sébastien, Mathieu, Patrick, Bossé, Yohan, Arsenault, Benoit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307014/
https://www.ncbi.nlm.nih.gov/pubmed/34357353
http://dx.doi.org/10.3390/metabo11070459