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HO-1 and Heme: G-Quadruplex Interaction Choreograph DNA Damage Responses and Cancer Growth

Many anti-cancer therapeutics lead to the release of danger associated pattern molecules (DAMPs) as the result of killing large numbers of both normal and transformed cells as well as lysis of red blood cells (RBC) (hemolysis). Labile heme originating from hemolysis acts as a DAMP while its breakdow...

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Detalles Bibliográficos
Autores principales: Canesin, Giacomo, Muralidharan, Anindhita Meena, Swanson, Kenneth D., Wegiel, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307061/
https://www.ncbi.nlm.nih.gov/pubmed/34359970
http://dx.doi.org/10.3390/cells10071801