Is Hypoxia a Factor Influencing PSMA-Directed Radioligand Therapy?—An In Silico Study on the Role of Chronic Hypoxia in Prostate Cancer

SIMPLE SUMMARY: Tumor hypoxia is considered a critical factor associated with the resistance of conventional radiotherapy, where the X-ray-induced free radicals lead to DNA damage in a manner that is strongly dependent on the tissue oxygenation. The emerging PSMA-directed radioligand therapy (RLT) e...

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Detalles Bibliográficos
Autores principales: Birindelli, Gabriele, Drobnjakovic, Milos, Morath, Volker, Steiger, Katja, D’Alessandria, Calogero, Gourni, Eleni, Afshar-Oromieh, Ali, Weber, Wolfgang, Rominger, Axel, Eiber, Matthias, Shi, Kuangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307065/
https://www.ncbi.nlm.nih.gov/pubmed/34298642
http://dx.doi.org/10.3390/cancers13143429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307065/
https://www.ncbi.nlm.nih.gov/pubmed/34298642
http://dx.doi.org/10.3390/cancers13143429

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