Intersection of Two Checkpoints: Could Inhibiting the DNA Damage Response Checkpoint Rescue Immune Checkpoint-Refractory Cancer?

SIMPLE SUMMARY: Immunotherapies have revolutionized the management of advanced stage cancer; however, not all patients benefit given many cancers are resistant to immune checkpoint inhibitors. To support rapid growth, malignant cells frequently bypass the cell cycle checkpoints that normally ensure...

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Detalles Bibliográficos
Autores principales: Goff, Peter H., Bhakuni, Rashmi, Pulliam, Thomas, Lee, Jung Hyun, Hall, Evan T., Nghiem, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307089/
https://www.ncbi.nlm.nih.gov/pubmed/34298632
http://dx.doi.org/10.3390/cancers13143415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307089/
https://www.ncbi.nlm.nih.gov/pubmed/34298632
http://dx.doi.org/10.3390/cancers13143415

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