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Chromenol Derivatives as Novel Antifungal Agents: Synthesis, In Silico and In Vitro Evaluation

Herein we report the synthesis of some new 1H-1,2,4-triazole functionalized chromenols (3a–3n) via tandem reactions of 1-(alkyl/aryl)-2-(1H-1,2,4-triazole-1-yl) with salicylic aldehydes and the evaluation of their antifungal activity. In silico prediction of biological activity with computer program...

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Detalles Bibliográficos
Autores principales: Zveaghintseva, Marina, Stingaci, Eugenia, Pogrebnoi, Serghei, Smetanscaia, Anastasia, Valica, Vladimir, Uncu, Livia, Ch. Kravtsov, Victor, Melnic, Elena, Petrou, Anthi, Glamočlija, Jasmina, Soković, Marina, Carazo, Alejandro, Mladěnka, Přemysl, Poroikov, Vladimir, Geronikaki, Athina, Macaev, Fliur Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307147/
https://www.ncbi.nlm.nih.gov/pubmed/34299579
http://dx.doi.org/10.3390/molecules26144304