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HDAC Inhibitors: Dissecting Mechanisms of Action to Counter Tumor Heterogeneity

SIMPLE SUMMARY: Tumor heterogeneity promotes the development of drug resistance in cancer. HDAC inhibitors modulate several processes that contribute to intra-tumoral heterogeneity. With careful consideration of the underlying biology, HDAC inhibitors can be utilized to improve therapeutic efficacy....

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Detalles Bibliográficos
Autores principales: Karagiannis, Dimitris, Rampias, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307174/
https://www.ncbi.nlm.nih.gov/pubmed/34298787
http://dx.doi.org/10.3390/cancers13143575