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HDAC Inhibitors: Dissecting Mechanisms of Action to Counter Tumor Heterogeneity
SIMPLE SUMMARY: Tumor heterogeneity promotes the development of drug resistance in cancer. HDAC inhibitors modulate several processes that contribute to intra-tumoral heterogeneity. With careful consideration of the underlying biology, HDAC inhibitors can be utilized to improve therapeutic efficacy....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307174/ https://www.ncbi.nlm.nih.gov/pubmed/34298787 http://dx.doi.org/10.3390/cancers13143575 |