Cholesterol is required for transcriptional repression by BASP1

Lipids are present within the cell nucleus, where they engage with factors involved in gene regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome packing in vitro, but its effects on specific transcriptional responses are not clear. Here, we show that the lipidated Wilm...

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Detalles Bibliográficos
Autores principales: Loats, Amy E., Carrera, Samantha, Fleming, Anna F., Roberts, Abigail R. E., Sherrard, Alice, Toska, Eneda, Moorhouse, Alexander J., Medler, Kathryn F., Roberts, Stefan G. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307447/
https://www.ncbi.nlm.nih.gov/pubmed/34266955
http://dx.doi.org/10.1073/pnas.2101671118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307447/
https://www.ncbi.nlm.nih.gov/pubmed/34266955
http://dx.doi.org/10.1073/pnas.2101671118

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