A Galantamine–Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells

Misfolded amyloid beta (Aβ) peptides aggregate and form neurotoxic oligomers. Membrane and mitochondrial damages, calcium dysregulation, oxidative stress, and fibril deposits are among the possible mechanisms of Aβ cytotoxicity. Galantamine (GAL) prevents apoptosis induced by Aβ mainly through the a...

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Detalles Bibliográficos
Autores principales: Mladenova, Kirilka, Stavrakov, Georgi, Philipova, Irena, Atanasova, Mariyana, Petrova, Svetla, Doumanov, Jordan, Doytchinova, Irini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307467/
https://www.ncbi.nlm.nih.gov/pubmed/34299209
http://dx.doi.org/10.3390/ijms22147592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307467/
https://www.ncbi.nlm.nih.gov/pubmed/34299209
http://dx.doi.org/10.3390/ijms22147592

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