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Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State

Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished only via tracer metabolism approaches that re...

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Detalles Bibliográficos
Autores principales: Ragavan, Mukundan, McLeod, Marc A., Giacalone, Anthony G., Merritt, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307483/
https://www.ncbi.nlm.nih.gov/pubmed/34357335
http://dx.doi.org/10.3390/metabo11070441