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Skeletal Deformities in Osterix-Cre;Tgfbr2(f/f) Mice May Cause Postnatal Death

Transforming growth factor β (TGFβ) signaling plays an important role in skeletal development. We previously demonstrated that the loss of TGFβ receptor II (Tgfbr2) in Osterix-Cre-expressing mesenchyme results in defects in bones and teeth due to reduced proliferation and differentiation in pre-oste...

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Detalles Bibliográficos
Autores principales: Corps, Kara, Stanwick, Monica, Rectenwald, Juliann, Kruggel, Andrew, Peters, Sarah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307487/
https://www.ncbi.nlm.nih.gov/pubmed/34202311
http://dx.doi.org/10.3390/genes12070975