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Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases

It was proposed that the last universal common ancestor (LUCA) evolved under high temperatures in an oxygen-free environment, similar to those found in deep-sea vents and on volcanic slopes. Therefore, spontaneous DNA decay, such as base loss and cytosine deamination, was the major factor affecting...

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Detalles Bibliográficos
Autores principales: Prorok, Paulina, Grin, Inga R., Matkarimov, Bakhyt T., Ishchenko, Alexander A., Laval, Jacques, Zharkov, Dmitry O., Saparbaev, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307549/
https://www.ncbi.nlm.nih.gov/pubmed/34202661
http://dx.doi.org/10.3390/cells10071591