Tumor Escape Phenotype in Bladder Cancer Is Associated with Loss of HLA Class I Expression, T-Cell Exclusion and Stromal Changes

Cancer eradication and clinical outcome of immunotherapy depend on tumor cell immunogenicity, including HLA class I (HLA-I) and PD-L1 expression on malignant cells, and on the characteristics of the tumor microenvironment, such as tumor immune infiltration and stromal reaction. Loss of tumor HLA-I i...

Descripción completa

Detalles Bibliográficos
Autores principales: Gil-Julio, Hernani, Perea, Francisco, Rodriguez-Nicolas, Antonio, Cozar, Jose Manuel, González-Ramirez, Amanda Rocío, Concha, Angel, Garrido, Federico, Aptsiauri, Natalia, Ruiz-Cabello, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307653/
https://www.ncbi.nlm.nih.gov/pubmed/34298868
http://dx.doi.org/10.3390/ijms22147248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307653/
https://www.ncbi.nlm.nih.gov/pubmed/34298868
http://dx.doi.org/10.3390/ijms22147248

Ejemplares similares