DNA Methylation and Intra-Clonal Heterogeneity: The Chronic Myeloid Leukemia Model

SIMPLE SUMMARY: In Chronic Myeloid Leukemia (CML), intra-clonal heterogeneity is a major factor in the response to tyrosine kinase inhibitors and in leukemia stem cell persistence. This intra-clonal heterogeneity could be partially explained by epigenetic abnormalities. This review focuses on DNA me...

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Detalles Bibliográficos
Autores principales: Lebecque, Benjamin, Bourgne, Céline, Vidal, Véronique, Berger, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307727/
https://www.ncbi.nlm.nih.gov/pubmed/34298798
http://dx.doi.org/10.3390/cancers13143587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307727/
https://www.ncbi.nlm.nih.gov/pubmed/34298798
http://dx.doi.org/10.3390/cancers13143587

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