Distinctive Properties and Powerful Neuromodulation of Na(v)1.6 Sodium Channels Regulates Neuronal Excitability

Voltage-gated sodium channels (Navs) are critical determinants of cellular excitability. These ion channels exist as large heteromultimeric structures and their activity is tightly controlled. In neurons, the isoform Na(v)1.6 is highly enriched at the axon initial segment and nodes, making it critic...

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Detalles Bibliográficos
Autores principales: Zybura, Agnes, Hudmon, Andy, Cummins, Theodore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307729/
https://www.ncbi.nlm.nih.gov/pubmed/34202119
http://dx.doi.org/10.3390/cells10071595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307729/
https://www.ncbi.nlm.nih.gov/pubmed/34202119
http://dx.doi.org/10.3390/cells10071595

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