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New Insights into Profibrotic Myofibroblast Formation in Systemic Sclerosis: When the Vascular Wall Becomes the Enemy

In systemic sclerosis (SSc), abnormalities in microvessel morphology occur early and evolve into a distinctive vasculopathy that relentlessly advances in parallel with the development of tissue fibrosis orchestrated by myofibroblasts in nearly all affected organs. Our knowledge of the cellular and m...

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Detalles Bibliográficos
Autores principales: Romano, Eloisa, Rosa, Irene, Fioretto, Bianca Saveria, Matucci-Cerinic, Marco, Manetti, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307837/
https://www.ncbi.nlm.nih.gov/pubmed/34202703
http://dx.doi.org/10.3390/life11070610