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NADPH Oxidase (NOX) Targeting in Diabetes: A Special Emphasis on Pancreatic β-Cell Dysfunction

In type 2 diabetes, metabolic stress has a negative impact on pancreatic β-cell function and survival (T2D). Although the pathogenesis of metabolic stress is complex, an imbalance in redox homeostasis causes abnormal tissue damage and β-cell death due to low endogenous antioxidant expression levels...

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Detalles Bibliográficos
Autores principales: Elumalai, Suma, Karunakaran, Udayakumar, Moon, Jun-Sung, Won, Kyu-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307876/
https://www.ncbi.nlm.nih.gov/pubmed/34206537
http://dx.doi.org/10.3390/cells10071573