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Reaction of Chalcones with Cellular Thiols. The Effect of the 4-Substitution of Chalcones and Protonation State of the Thiols on the Addition Process. Diastereoselective Thiol Addition

Several biological effects of chalcones have been reported to be associated with their thiol reactivity. In vivo, the reactions can result in the formation of small-molecule or protein thiol adducts. Both types of reactions can play a role in the biological effects of this class of compounds. Progre...

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Detalles Bibliográficos
Autores principales: Kenari, Fatemeh, Molnár, Szilárd, Perjési, Pál
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308006/
https://www.ncbi.nlm.nih.gov/pubmed/34299607
http://dx.doi.org/10.3390/molecules26144332