Metformin and Niclosamide Synergistically Suppress Wnt and YAP in APC-Mutated Colorectal Cancer

SIMPLE SUMMARY: Hyperactivation of the canonical Wnt and inactivation of the Hippo pathway are well-known genetic backgrounds for familial adenomatosis polyposis (FAP) and colorectal cancer (CRC), although the reciprocal regulation between those pathways is not yet clear. In this study, we found tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Hee Eun, Seo, Yoojeong, Yun, Jun Seop, Song, Sang Hyun, Han, Dawool, Cho, Eunae Sandra, Cho, Sue Bean, Jeon, Yoon, Lee, Ho, Kim, Hyun Sil, Kang, Joyeon, Yook, Jong In, Kim, Nam Hee, Kim, Tae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308039/
https://www.ncbi.nlm.nih.gov/pubmed/34298652
http://dx.doi.org/10.3390/cancers13143437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308039/
https://www.ncbi.nlm.nih.gov/pubmed/34298652
http://dx.doi.org/10.3390/cancers13143437

Ejemplares similares