Allosteric Modulation of GSK-3β as a New Therapeutic Approach in Limb Girdle Muscular Dystrophy R1 Calpain 3-Related

Limb-girdle muscular dystrophy R1 calpain 3-related (LGMDR1) is an autosomal recessive muscular dystrophy produced by mutations in the CAPN3 gene. It is a rare disease and there is no cure or treatment for the disease while the pathophysiological mechanism by which the absence of calpain 3 provokes...

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Detalles Bibliográficos
Autores principales: Rico, Anabel, Guembelzu, Garazi, Palomo, Valle, Martínez, Ana, Aiastui, Ana, Casas-Fraile, Leire, Valls, Andrea, López de Munain, Adolfo, Sáenz, Amets
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308041/
https://www.ncbi.nlm.nih.gov/pubmed/34298987
http://dx.doi.org/10.3390/ijms22147367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308041/
https://www.ncbi.nlm.nih.gov/pubmed/34298987
http://dx.doi.org/10.3390/ijms22147367

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