Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

SIMPLE SUMMARY: A type of DNA mismatch repair defect known as “elevated microsatellite alterations at selected tetranucleotide repeats” (EMAST) is found across many different cancers. Tetranucleotide microsatellite instability, which is caused by MSH3 mismatch repair gene/protein loss-of-function, s...

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Detalles Bibliográficos
Autores principales: Meessen, Sabine, Currey, Nicola, Jahan, Zeenat, Parker, Hannah W., Jenkins, Mark A., Buchanan, Daniel D., Hopper, John L., Segelov, Eva, Dahlstrom, Jane E., Kohonen-Corish, Maija R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308094/
https://www.ncbi.nlm.nih.gov/pubmed/34298744
http://dx.doi.org/10.3390/cancers13143529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308094/
https://www.ncbi.nlm.nih.gov/pubmed/34298744
http://dx.doi.org/10.3390/cancers13143529

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