Induction of Glutathione Synthesis Provides Cardioprotection Regulating NO, AMPK and PPARa Signaling in Ischemic Rat Hearts

Glutathione (GSH) is essential for antioxidant defence, and its depletion is associated with tissue damage during cardiac ischemia-reperfusion (I/R). GSH is synthesized by the glutamate-cysteine ligase enzyme (GCL) from L-cysteine, which alternatively might be used for hydrogen sulfide production by...

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Detalles Bibliográficos
Autores principales: Goshovska, Yulia V., Fedichkina, Raisa A., Balatskyi, Volodymyr V., Piven, Oksana O., Dobrzyn, Pawel, Sagach, Vadym F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308105/
https://www.ncbi.nlm.nih.gov/pubmed/34209822
http://dx.doi.org/10.3390/life11070631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308105/
https://www.ncbi.nlm.nih.gov/pubmed/34209822
http://dx.doi.org/10.3390/life11070631

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