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Synthesis and Characterization of a “Clickable” PBR28 TSPO-Selective Ligand Derivative Suitable for the Functionalization of Biodegradable Polymer Nanoparticles

Reactive microgliosis is a pathological hallmark that accompanies neuronal demise in many neurodegenerative diseases, ranging from acute brain/spinal cord injuries to chronic diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD) and age-related dementia. One strategy to ass...

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Detalles Bibliográficos
Autores principales: Auriemma, Renato, Sponchioni, Mattia, Capasso Palmiero, Umberto, Rossino, Giacomo, Rossetti, Arianna, Marsala, Andrea, Collina, Simona, Sacchetti, Alessandro, Moscatelli, Davide, Peviani, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308144/
https://www.ncbi.nlm.nih.gov/pubmed/34203263
http://dx.doi.org/10.3390/nano11071693