Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia

Myelodysplastic Syndromes (MDSs) affect the elderly and can progress to Acute Myeloid Leukemia (AML). Epigenetic alterations including DNA methylation and chromatin modification may contribute to the initiation and progression of these malignancies. DNA hypomethylating agents such as decitabine and...

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Detalles Bibliográficos
Autores principales: Sorrentino, Vincent G., Thota, Srijan, Gonzalez, Edward A., Rameshwar, Pranela, Chang, Victor T., Etchegaray, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308509/
https://www.ncbi.nlm.nih.gov/pubmed/34358067
http://dx.doi.org/10.3390/ph14070641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308509/
https://www.ncbi.nlm.nih.gov/pubmed/34358067
http://dx.doi.org/10.3390/ph14070641

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